Both smallpox and monkeypox viruses belong to the Orthopoxvirus genus of the Poxviridae family, so the smallpox vaccine also provides cross-protection against monkeypox. The vaccine helps the immune system recognize and fight the virus.

Vaccination significantly reduces the risk of developing a severe form of the disease.

A third-generation smallpox vaccine, Imvanex, is registered in the European Union and is given to adults to protect against smallpox.

The availability of this vaccine is limited, so in order to allow the rapid control of outbreaks, the US-made vaccine „Jynneos“ is also  allowed for use in the European Union.

Last updated: 20-11-2023